PROGRAM & AGENDA

Monday, January 2, 2023

Tuesday, January 3, 2023

Keynote: Cell morphological control of oncogenic signals
Gaudenz Danuser, UT Southwestern Medical Center

Rising star award: AP-1 transcription factor network controls diverse patterns of cell state plasticity
Mohammad Fallahi-Sichani, University of Virginia

Postdoc researcher travel award: Spatial multi-omic profiling of human hippocampus reveals region-specific alterations in major depressive disorder
Yang Xiao, Columbia University

Selected short talk: A chicken and egg challenge: Roles of cardiac fibroblasts and cardiomyocytes in age-related heart failure
Justin Cooper-White, University of Queensland

Selected short talk: Inflammatory serum factors from aortic valve stenosis patients drive sex differences in valve myofibroblasts
Brian Aguado, University of California, San Diego

Rising star award: Simulated microgravity enhances adipocyte maturation and glucose uptake via increased cortical actin remodeling
Evangelia Bellas, Temple University

Lightning talk: An explainable AI approach to differentiate breast cancer morphologies between racial groups
Heather Dunn, Clemson University

Lightning talk: Fluid shear stress in ovarian cancer metastasis via glycocalyx modulation
Eric Horst, University of Michigan, Ann Arbor

Lightning talk: EB3 acts as a link between microtubules and calcium dysregulation in traumatic brain injury
Michael Hanna, New Jersey Institute of Technology

Lightning talk: Conductive electrospun polymer platforms improve stem cell-derived cardiomyocyte function and maturation
Giselle Gonzalez, University of California, San Diego

Poster Viewing I & Coffee Break (Room Location: Indian Wells LM)

Session II: Cell state transitions and cell competition in development and diseases - II
Chairs: Ngan F. Huang (Stanford University) & Deborah Leckband (University of Illinois Urbana-Champaign)

Invited talk:Race CAR-M, enhanced cancer immunotherapy based on insights from Drosophila
Denise Montell, University of California, Santa Barbara

Selected short talk: Peristalsis-associated mechanotransduction drives malignant progression of colorectal cancer
Shreya Raghavan, Texas A&M University

Postdoc researcher travel award: Cooperative phagocytosis of cohesive cancer cell targets by phase separating macrophages
Lawrence Dooling, University of Pennsylvania

Selected short talk: Macrophage-targeted drug delivery for systemic and local immunotherapies
Christopher Rodell, Drexel University

Postdoc researcher travel award:Type-2 functionality regulates Tim-3+ dysfunctional effector CAR T cells in association with 8-year remission in patients with B-ALL 

Zhiliang Bai, Yale University

12:20- 12:50pm

Chris Jacobs Award for Excellence in Leadership Presentation
Introduction by Deborah Leckband, University of Illinois Urbana-Champaign

Title: Closing the biomedical innovation gap: A critical need for diversifying the biomedical engineering pipeline
Lola Eniola-Adefeso, University of Michigan, Ann Arbor

Poster viewing II & Refreshment break (Room Location: Indian Wells LM)

Wednesday, January 4, 2023

Keynote: Discovery of an endogenous cellular pathway that regulates transcriptional noise to promote cell-fate specification
Leor Weinberger, University of California, San Francisco

Invited talk: Genome replication as origin of regulatory variation and epigenetic drift
Tim Downing, University of California, Irvine

Rising star award: Engineering high-precision, dynamic genetic control systems for cellular reprogramming
Katie Galloway, Massachusetts Institute of Technology

Rising star award: Single-molecule detection of pseudouridine modifications in the human transcriptome
Sara Rouhanifard, Northeastern University

Selected short talk: Genetically encoded detection and guidance of cell state transitions via endoribonuclease mediated microRNA sensors
Lei Wang, Massachusetts Institute of Technology

Lightning talk: Woven bone organoids as a therapy model for in vivo bone regeneration
Sai Sreenivasamurthy, State University of New York at Stony Brook

Lightning talk: DNA-enhanced CuAAC ligand enables live-cell detection of intracellular biomolecules
Keqing Nian, Northeastern University

Lightning talk: Deciphering impacts of physiological-stimuli on neuroepithelial development in forebrain organoids
Marie Payne, University of California, Los Angeles

Poster viewing III & Coffee Break (Room Location: Indian Wells LM)

Sponsored by:

Center for Engineering MechanoBiology (CEMB)

Session IV: Developmental biomechanics
Chairs: Nadeen O. Chahine (Columbia University) & Yi-Xian Qin (State University of New York at Stony Brook)

Invited talk: MYH7 mutations induce changes in single cell mechanobiology
Beth Pruitt, University of California, Santa Barbara

Rising star award: In vivo study and synthetic engineering of mechanical rules for kidney tubule morphogenesis
Alex Hughes, University of Pennsylvania

Postdoc researcher travel award: Understanding the mechanics of human somitogenesis through in vitro and theoretical models
Yue Liu, University of Michigan, Ann Arbor

Selected short talk: Biophysical modeling of the human T cell repertoire for optimized immunotherapy
Jason George, Texas A&M University

Selected short talk: Exercise-mediated biochemical signaling guides maturation and repair of skeletal muscle
Ritu Raman, Massachusetts Institute of Technology

12:25- 12:40 pm

Postdoc researcher travel award: Engineering mRNA therapies for central nervous system disorders
Saigopalakrishna Yerneni, Carnegie Mellon University

Gala Dinner (Updated Room Location: Indian Wells IJK)

Please note, this room has changed from what is listed in the pdf agenda. 

(cash bar for alcoholic beverages and sodas)

2022 Shu Chien Achievement Award Presentation
Introduction by Brent Hoffman (Duke University), with an introduction video from Shu Chien

The interplay between tissue tension and tumor immunity
Valerie M. Weaver, University of California, San Francisco

2023 Shu Chien Achievement Award Presentation
Introduction by Deborah Leckband (University of Illinois Urbana-Champaign), with an introduction video from Shu Chien

Regenerative engineering: A convergence field addressing global grand challenges in health
Cato T. Laurencin, University of Connecticut

Thursday, January 5, 2023

Registration Open (Room Location: Registration Counter #1(K)

Session V: Links between biophysical and biochemical states
Chairs: Stephanie I. Fraley (University of California, San Diego) & Dennis Discher (University of Pennsylvania)

Momentum Award (Sponsored by APL Publishing) Presentation
Introduction by Deborah Leckband, University of Illinois Urbana-Champaign

Physical sciences approaches to analyze tumor-associated ECM dynamics
Claudia Fischbach, Cornell University

Invited talk: Modeling in medicine: Case studies in cancer and COVID-19
David Odde, University of Minnesota

Rising star award: Hydrogels with tunable stress relaxation regulate the immunosuppressive capacity of mesenchymal stem cells
Luo Gu, Johns Hopkins University

Rising star award: Multicellular 3D lung models reveal alveolar epithelial cells and microenvironmental stiffness synergistically drive fibroblast activation in vitro
Chelsea Magin, University of Colorado, Denver

Lightning talk: Single cell force is a clinically relevant immune-modulated biophysical biomarker for bleeding severity
Oluwamayokun Oshinowo, Medical College of Georgia & Georgia Institute of Technology

Lightning talk: Leveraging hydrogel viscoelasticity and heterogeneity to promote cell migration in meniscal repair
Karen Xu, University of Pennsylvania

Lightning talk: Piezo1 overexpression promotes aberrant mechanosensation in aged vascular smooth muscle cells
Ngoc (Kate) Luu, New York University

Lightning talk: Physical modeling to optimize design of therapeutic T cells
Roberto Alonso Matilla, University of Minnesota

Poster viewing V & coffee break (Room Location: Indian Wells LM)

Invited talk: Microenvironmental regulation of vascular formation and function
Sharon Gerecht, Duke University

Invited talk: Engineering the heterogeneity of pluripotent stem cells for organoid development
Todd McDevitt, Sana Biotech.

Rising star award: It takes a heart to make the lung: Recapitulate human cardio-pulmonary co-development using stem cells
Xi Ren, Carnegie Mellon University

Postdoc researcher travel award: A fully patterned human neural tube model for studying human neurodevelopment and diseases
Xufeng Xue, University of Michigan, Ann Arbor

Selected short talk: Engineering functional biomaterials with stem cells for therapeutic lymphangiogenesis
Donny Hanjaya-Putra, University of Notre Dame

Postdoc researcher travel award: Endogenous optical markers profile the metabolic continuum of stem cell differentiation
Hao Zhou, University of Southern California

Selected short talk: Spatially patterned synthetic cues for controlled co-differentiation of vascularized muscle tissues
Tyler Hoffman, University of California, Los Angeles

Sponsor special talk: California Institute for Regenerative Medicine

Landing a Job in Industry – Insights from the MedTech Sector

Poster viewing VI, Networking, with Refreshment Break (Room Location: Indian Wells LM)

Friday, January 6, 2023

Continental Breakfast (Room Location: 18th Hole Terrace & LM Foyer)

Sponsored by:

Penn Engineering

Keynote: Directed evolution of new adeno - associated viral vectors for clinical gene therapy
David Schaffer, University of California, Berkeley

Rising star award: Mapping in vivo journey of DNA nanodevice using imaging and single-cell techniques
Leo YT Chou, University of Toronto

Rising star award: Ultrasound-responsive 3D culture systems for remote manipulation of cell signaling
Carolyn Schutt Ibsen, Oregon Health & Science University

Selected short talk: Reshaping the cellular transcriptome by transcription factor delivery
Irtisha Singh, Texas A&M University

Selected short talk: Decellularized cartilage and auricular progenitor cells for airway repair in a rabbit model
Riccardo Gottardi, University of Pennsylvania

Postdoc researcher travel award: Monitoring of stem cell location and viability in vivo via cell nanoengineering and photoacoustics
Jinhwan Kim, Georgia Institute of Technology

Selected short talk: Spatially resolved epigenomic profiling of single cells in complex tissues
Cheen Euong Ang, Harvard University

Coffee break (Room Location: Indian Wells LM)

Sponsored by: 

Journal of Cell Science

Invited talk: Multi-cellular aggregate formation in ovarian cancer
Pam Kreeger, University of Wisconsin, Madison

Invited talk: Spatial multi-omics driving the next wave of biomedical research revolution
Rong Fan, Yale University

Rising star award: Single cell spatial metabolomics reveals immunometabolism in tissues
Ahmet Coskun, Georgia Institute of Technology & Emory University

Rising star award: Engineer CAR-neutrophils from human pluripotent stem cells for targeted chemoimmunotherapy against glioblastoma
Xiaoping Bao, Purdue University

Rising star award: Enhancing gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments anti-tumor immune response
Quanyin Hu, University of Wisconsin, Madison

Selected short talk: From state to rate: Transforming how monocyte differentiation and polarization are characterized
Elizabeth Wayne, Carnegie Mellon University